澳门在线威尼斯官方-威尼斯威尼斯国际网址

澳门在线威尼斯官方
师资力量

杨宇东     副教授

研究方向:有机金属化学、多环芳烃合成

联系方式:028-85418887          Email:yangyudong@scu.edu.cn

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简历

2016.10至今 澳门在线威尼斯官方,副教授

2014.7—2016.10   澳门在线威尼斯官方,讲师,合作导师:游劲松教授

2011.4—2014.3   名古屋工业大学,未来材料创成工学专业,博士,导师:Norio Shibata教授

2007.7—2010.7   北京化工大学,化学工程与技术专业,硕士,导师:杜洪光教授

2003.9—2007.7   北京化工大学,应用化学专业,学士

主要研究方向

(1)惰性化学键活化的理论与策略研究

2具有新颖结构的多环芳烃的设计合成及光电性能研究

3)有机光电材料的合成化学基础

主要工作业绩

杨宇东博士一直从事过渡金属催化的惰性化学键活化,特别是C–H键直接高效、高选择性转化方面的研究,发展了多种基于过渡金属催化C?H键活化构筑有机π共轭骨架的新方法和新策略,并开发它们在有机光电转化材料、分子探针以及细胞、组织成像等领域的应用。基于螯合导向的策略,实现了多种(杂)芳烃之间的C–H/C–H氧化交叉偶联反应及(杂)芳烃与炔烃之间的氧化环化反应,为联(杂)芳烃及多环稠合骨架的构筑提供了简洁、高效的新方法;发展了一系列基于选择性C–H直接转化的三氟甲基化及三氟甲硫基化方法,为含氟芳烃、杂芳烃、酰胺及β-酮酯类化合物的合成提供了新的高效途径。多篇工作入选高被引论文和热点论文。首次分离得到了(杂)芳烃氧化交叉偶联反应中的双(杂)芳基金属中间体,为氧化交叉偶联反应的机理研究提供了重要依据 (ACS Catal. 2019, 9, 6372),该工作被评为当月的the most read article;撰写了近年来(杂)芳环之间的C–H/C–H氧化交叉偶联反应的评述性文章 (Chem. Rev., 2017, 117, 8787);撰写了基于弱导向策略的芳环C?H键与炔之间的环化反应的Feature Article (Chem. Commun., 2016, 52, 2872),该文章入选most cited features from 2016, 2017;撰写了Wiley出版社的《Transition Metal-Catalyzed   Heterocycle Synthesis via C?H Activation》一书中第三章,先容基于钯催化C–H键活化的策略合成含氧杂环方面的研究成果;开发了一种基于高碘化合物的三氟甲硫基化试剂,该试剂目前已经商业化,可在TCI等企业购买 (TCI产品编号:P2143)。目前,已在Chem. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem. Commun.Org. Lett.等期刊发表SCI论文30余篇;参与编写专著1部。

 

主要奖励和荣誉:

2018.11

澳门在线威尼斯官方首届“探究式-小班化”教学竞赛三等奖

2018.6

澳门在线威尼斯官方2017-2018年度本科优秀实习引导教师二等奖

2018.6

澳门在线威尼斯官方2017-2018年度本科优秀生产实习队三等奖

2017.12

澳门在线威尼斯官方2016年度本科教学课堂教学质量优秀奖

2017.6

澳门在线威尼斯官方2016-2017年度化学专业优秀生产实习队二等奖

2010.10-2014.03

日本文部科学省奖学金

2008.11

第六届中国挑战杯创业计划竞赛国家级银奖

2008.06

第五届挑战杯首都大学生创业计划竞赛特等奖

2008.04

北京化工大学第四届寰球杯创业计划与科技创新大赛一等奖

2007.06

北京市优秀毕业生

 

代表性成果 (获奖成果、专著、论文、专利)

 

一、代表性论文:

1. Boya Feng, Yudong Yang,* Jingsong You.* Palladium-catalyzed denitrative Sonogashira-type cross-coupling of nitrobenzenes with terminal alkynes. Chem. Commun. 2020, 56 (5), 790–793. (Publication Date:2020-01-16)

2. Min Zhang, Anping Luo, Yang Shi, Rongchuan Su, Yudong Yang,* Jingsong You.* F+ Reagent-Promoted Pd-Catalyzed C7?H Arylation of 1-Naphthamides. ACS Catal. 2019, 9 (12), 11802–11807. (Publication Date:2019-12-06)

3.  Shuyou Chen, Min Zhang, Rongchuan Su, Xingyu Chen, Boya Feng, Yudong Yang,* and Jingsong You*. C2/C4 Regioselective Heteroarylation of Indoles by Tuning C–H Metalation   Modes. ACS Catal. 2019, 9 (7), 6372–6379. (Publication Date: 2019-07-05). (selected as the most read article)

4. Jiao Liu, Hao Fang, Rui Cheng, Zhishuo Wang, Yudong Yang,* and Jingsong You.* Cascade intramolecular imidoylation and C–H   activation/annulation of benzimidoyl chlorides with alkynes: one-pot   synthesis of 7H-dibenzo[de,h]quinoline analogues. Chem. Commun. 2019, 55 (49), 7097–7100. (Publication Date: 2019-06-21).

5. Yang Shi, Jiahui Liu, Yudong Yang,* and Jingsong You*. General rhodium-catalyzed oxidative cross-coupling reactions between anilines: synthesis of unsymmetrical 2,2’-diaminobiaryls. Chem.Commun. 2019, 55 (38), 5475–5478. (Publication Date: 2019-05-11).

 

6. Xingrong Liao, Deping Wang, Yueyuan Huang, Yudong Yang,* and Jingsong You.* Highly Chemo-, Regio- and E/Z-Selective Intermolecular Heck-Type Dearomative [2+2+1]  Spiroannulation of Alkyl Bromoarenes with Internal Alkynes. Org. Lett.   2019, 21 (4), 1152–1155. (Publication Date: 2019-02-15).

7. Zhigang Wang, Mufan Yang, and Yudong Yang.* Ir(III)-Catalyzed Oxidative Annulation of Phenylglyoxylic Acids with Benzo[b]thiophenes. Org. Lett. 2018, 20 (10), 3001–3005. (Publication Date: 2018-05-18).

8.  Shiping Yang, Boya Feng, Yudong Yang.* Rh(III)-Catalyzed Direct ortho-Chalcogenation   of Phenols and Anilines. J. Org. Chem. 2017, 82 (23), 1243012438. (Publication Date: 2017-12-01)

9. Yudong Yang, Jingbo Lan, Jingsong You.* Oxidative C–H/C–H Coupling   Reactions between Two (Hetero)arenes. Chem. Rev. 2017,   117(13), 87878863. (ESI高被引论文)

10. Yudong Yang, Kaizhi Li, Yangyang Cheng, Danyang Wan, Mingliang Li,   Jingsong You.* Rhodium-catalyzed annulation of arenes with alkynes through   weak chelation-assisted C–H activation. Chem.   Commun. 2016, 52, 2872–2884. (Most cited Features from 2016,   2017)

11.Yang Liu, Yudong Yang*, Yang Shi, Xiaojie   Wang, Luoqiang Zhang, Yangyang Cheng, Jingsong You.* Rhodium-Catalyzed   Oxidative Coupling of Benzoic Acids with Terminal Alkynes: An Efficient   Access to 3-Ylidenephthalides. Organometallics 2016, 35(10), 13501353.

12.  Danyang Wan, Yudong Yang,* Xingyan Liu,   Mingliang Li, Siling Zhao, Jingsong You.* Radical Cyclization of   Arenesulfonyl Chlorides and Alkynes: A Rapid Access to π-Conjugated   Benzothiophenes. Eur. J. Org. Chem. 2016, 55–59. (Most Accessed paper)

13.  Chunxia Wang, Yudong Yang*, Dekun Qin,   Zhen He, Jingsong You.* Copper-Catalyzed Intramolecular Dehydrogenative   Amidation of Unactivated C(sp3)–H Bonds Using O2 as the   Sole Oxidant. J. Org. Chem., 2015, 80(16), 8424–8429.

14.  Yu-Dong Yang, Etsuko Tokunaga, Hidehiko Akiyama, Norimichi Saito, Norio Shibata.* Bis(pentafluorosulfanyl)phenyl   Azide as an Expeditious Tool for Click Chemistry toward Antitumor   Pharmaceuticals. ChemMedChem 2014, 9(5), 913917.

15. Yu-Dong Yang, Ayaka Azuma, Etsuko Tokunaga, Mikio Yamasaki, Motoo   Shiro, Norio Shibata, “Trifluoromethanesulfonyl hypervalent iodonium ylide   for copper-catalyzed trifluoromethylthiolation of enamines, indoles, and   β-keto esters”, J. Am. Chem. Soc. 2013, 135(24), 87828785. (ESI高被引论文)

16.  Yu-Dong Yang, Kanji Iwamoto, Etsuko Tokunaga, Norio Shibata,   “Transition-metal-free oxidative trifluoromethylation of unsymmetrical   biaryls with trifluoromethanesulfinate”, Chem.   Commun. 2013, 49, 55105512.

17.  Yu-Dong Yang, Xu Lu, Guokai Liu, Etsuko Tokunaga, Seiji Tsuzuki, Norio   Shibata, “Cation versus radical: studies on the C/O regioselectivity in   electrophilic tri-, di, and monofluoromethylations of β-keto esters”, ChemistryOpen 2012,   1(5), 221226.

二、专著:

1.  Yudong Yang, Jingsong You, “Pd-Catalyzed Synthesis of   Oxygen-Containing Heterocycles”. In “Transition Metal-Catalyzed Heterocycle Synthesis via C–H   Activation” (Ed. Xiao-Feng. Wu), Wiley, Weinheim,   Germany, 2016, pp6589.

 

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